I gangværende Lumoral studier

Her er oversigten over studier med Lumoral per april 2024

Ongoing and planned studies

Periodontitis / Oral Hygiene

KHE2021 Metro / HOPE-CP - Periodontitis stage 1-3
• Timo Sorsa, Saila Pakarinen, Hanna-Mari Välimaa, Marja Noponen, Heikki Alapulli, Petri Auvinen
• 100+100 patients
• Sponsored, prospective, randomized
• Started: March 2022
• ClinicalTrials.gov ID: NCT05278416
• Preliminary results: https://doi.org/10.3390/dj10110206

LumoNorth2022 - Periodontitis stage 1-3
• Timo Sorsa, Paula Tegelberg, Meeri Ojala, Merja Ylipalosaari, Jori Lindroth, Petri Auvinen
• 45+45 patients
• Sponsored, prospective randomized, multicenter
• Started: Jan 2023
• ClinicalTrials.gov ID: NCT05425784

THSS1 - Smoking periodontitis patients
• Dimitra Sakellari, Timo Sorsa, Chrysoula Vakaki, Aikaterini- Elisavet Doufexi, Ismo Räisänen, Tommi Pätilä
• 30+30 patients
• Investigator-initiated, prospective, randomized, blinded
• Started Jan 2023
• ClinicalTrials.gov ID: NCT05962801

LumoKaunas2023, Periodontitis stage 3-4
• Ingrida Marija Pacauskienė, Nomeda Basevičienė, Vita Mačiulskienė, Raimonda Guntulytė, Alma Pranckevičienė, Renata Šadzevičienė, Petri Auvinen, Ismo Räisänen, Timo Sorsa
• Sponsored, prospective, randomized
• Started June 2023
• ClinicalTrials.gov ID: NCT05698823

LumoKoti, oral hygiene with elderly people living at home or at care home
• Timo Sorsa, Harry Niskanen, Pekka Kallio, Tommi Pätilä, Katja Gustafsson, Karim Abdalla
• Investigator-initiated, prospective, randomized
• Estimated start: Q2-Q3/2024
• ClinicalTrials.gov ID: TBA

Peri-implant disease

IS-2022 Enhanced oral hygiene effect on the implant success rate
• Hellevi Ruokonen, Karita Nylund, Timo Sorsa, Tommi Pätilä, Patricia Stoor, Nina-Li Avellán, Kirsten Besuch, Viivi Mattila, Petri Auvinen
• Investigator-initiated, prospective, randomized
• Started: Sep 2022

IS-TRE Prevention of peri-implant diseases
• Hanna Lähteenmäki, Timo Sorsa, Tommi Pätilä, Ismo Räisänen
• Investigator-initiated, prospective, randomized
• Study ended: July 2023
• Study report by Q2/2024
• ClinicalTrials.gov ID: NCT05871229

Severe peri-implantitis
• Nilminie Rathnayake, Timo Sorsa, Taina Tervahartiala, Akke Kumlien, Tommi Pätilä
• Investigator-initiated, prospective, randomized
• Estimated start: Q1/2024
• ClinicalTrials.gov ID: NCT06017817

Immunologically mediated mucocutaneous diseases

OLP-01TRE Treatment of oral lichen planus
• Anna Maria Heikkinen, Kati Ylä-Tuuhonen, Timo Sorsa, Jaana Hagström, Ulla Kotiranta, Taina Tervahartiala, Esko Kankuri, Outi Majala
• Sponsored, prospective, randomized
• Started: Jan 2023
• ClinicalTrials.gov ID: NCT05401201

Orthodontics

CLEAN-BRACKET Fixed orthodontic treatment in adolescents
• Ann-Marie Roos Jansåker, Katja Elses, My Blomqvist, Petri Auvinen
• Sponsored, prospective, randomized
• Started: Nov 2023
• ClinicalTrials.gov ID: NCT05825742

LumOsteo Prevention of osteolysis after dental implant surgery
• Pekka Kallio, Timo Strandén
• Investigator-initiated, prospective, randomized
• Estimated start: Q1/2024
• ClinicalTrials.gov ID: NCT06041828

Other

RSAA2021 Enhanced oral hygiene on elderly care home residents
• Riitta Saarela, Tommi Pätilä, Timo Sorsa, Jaana Helenius-Hietala, Anna Maria Heikkinen, Saila Pakarinen, Sakari Nikinmaa, Taina Tervahartiala, Sanna Korte, Wilma Romppanen, Tuuli Seitsamo
• Investigator-initiated, prospective, randomized
• Started: September 2022
• ClinicalTrials.gov ID: NCT05853679

Cleft palate operations - Enhanced oral hygiene
• Elisa Ronkainen, Juho Suojanen, Junnu Leikola, Arja Heliövaara
• Investigator-initiated, prospective
• Started: 2020

LumoPrevent / Targeting of Preventive Treatment for Adolescents at Risk of Oral Diseases
• Anna Maria Heikkinen, Milla Sarja, Teija Raivisto, Ismo Räisänen, Tommi Pätilä, Timo Sorsa, Saila Pakarinen
• Investigator-initiated, prospective, randomized
• Estimated start: Q2/2024
• ClinicalTrials.gov ID: NCT06286501

APDT-T2D, management and prevention of periodontitis symptoms in diabetic patients
• Anna Maria Heikkinen, Patrick Saikkonen, Miia Ehrnrooth, Timo Sorsa, Andreas Pfuetzner, Marko Helenius, Pirkko Pussinen, Atte Vadén, Tommi Pätilä, Timo Kauppila
• Investigator-initiated, prospective, randomized
• Estimated start: Q3/2024
• ClinicalTrials.gov ID: TBA